{"id":724,"date":"2023-03-17T15:47:21","date_gmt":"2023-03-17T14:47:21","guid":{"rendered":"http:\/\/apheresis-therapy.eu\/?page_id=724"},"modified":"2025-05-28T19:46:28","modified_gmt":"2025-05-28T17:46:28","slug":"lipid-apheresis","status":"publish","type":"page","link":"https:\/\/apherese-kortumpark.de\/en\/lipid-apheresis\/","title":{"rendered":"Lipid-Apheresis"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_section-dd4a0365af585a28765fef9382214fab\">\n.avia-section.av-av_section-dd4a0365af585a28765fef9382214fab{\nmargin-top:50px;\nmargin-bottom:50px;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-av_section-dd4a0365af585a28765fef9382214fab main_color avia-section-no-padding avia-no-border-styling  avia-builder-el-0  avia-builder-el-no-sibling  avia-bg-style-scroll container_wrap fullsize'  ><div class='container av-section-cont-open' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-724'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-bcda83ce7e5b941473874cd0da31d58a\">\n#top .av-special-heading.av-av_heading-bcda83ce7e5b941473874cd0da31d58a{\npadding-bottom:50px;\n}\nbody .av-special-heading.av-av_heading-bcda83ce7e5b941473874cd0da31d58a .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-bcda83ce7e5b941473874cd0da31d58a .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-bcda83ce7e5b941473874cd0da31d58a av-special-heading-h2 blockquote modern-quote  avia-builder-el-1  el_before_av_one_half  avia-builder-el-first '><h2 class='av-special-heading-tag'  itemprop=\"headline\"  >Lipidapheresis<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<div class='flex_column av-av_one_half-516b7eac7a9c6cd1b746245801c7486c av_one_half  avia-builder-el-2  el_after_av_heading  el_before_av_one_half  first flex_column_div '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_hr-decdff0fbf8f75d0be96725a83269fb0\">\n#top .hr.hr-invisible.av-av_hr-decdff0fbf8f75d0be96725a83269fb0{\nheight:10px;\n}\n<\/style>\n<div  class='hr av-av_hr-decdff0fbf8f75d0be96725a83269fb0 hr-invisible  avia-builder-el-3  el_before_av_image  avia-builder-el-first '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_image-ad33297f0e69cd02722629186362d302\">\n.avia-image-container.av-av_image-ad33297f0e69cd02722629186362d302 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-av_image-ad33297f0e69cd02722629186362d302 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-av_image-ad33297f0e69cd02722629186362d302 av-styling- av-hover-grow avia_animated_image av-animated-when-visible-95 pop-up avia-align-left  avia-builder-el-4  el_after_av_hr  avia-builder-el-last '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-690 avia-img-lazy-loading-not-690 avia_image ' src=\"https:\/\/apherese-kortumpark.de\/wp-content\/uploads\/apherese-behandlung-1.jpg\" alt='' title='Apherese-Behandlungspl\u00e4tze'  height=\"600\" width=\"800\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/apherese-kortumpark.de\/wp-content\/uploads\/apherese-behandlung-1.jpg 800w, https:\/\/apherese-kortumpark.de\/wp-content\/uploads\/apherese-behandlung-1-300x225.jpg 300w, https:\/\/apherese-kortumpark.de\/wp-content\/uploads\/apherese-behandlung-1-768x576.jpg 768w, https:\/\/apherese-kortumpark.de\/wp-content\/uploads\/apherese-behandlung-1-705x529.jpg 705w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/div><\/div><\/div><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_half-e671fab5613f317ef63eb9ab712c64a3\">\n.flex_column.av-av_one_half-e671fab5613f317ef63eb9ab712c64a3{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-av_one_half-e671fab5613f317ef63eb9ab712c64a3 av_one_half  avia-builder-el-5  el_after_av_one_half  el_before_av_one_half  flex_column_div av-zero-column-padding '     ><p><section  class='av_textblock_section av-av_textblock-7a1af7d8f9790576b1769c0a9f0449ed'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Individuals with <strong>elevated blood lipids<\/strong> \u2013 especially <strong>Lipoprotein(a)<\/strong> and <strong>LDL cholesterol<\/strong> \u2013 are at significantly increased risk for cardiovascular diseases such as <strong>heart attack<\/strong>, <strong>stroke<\/strong>, or <strong>aortic valve stenosis<\/strong>. Often, these conditions are caused by f<strong>amilial hypercholesterolemia<\/strong> or <strong>persistent lipid metabolism disorders<\/strong>.<\/p>\n<p>When <strong>lifestyle changes<\/strong> and <strong>medications<\/strong> such as <strong>statins<\/strong>, <strong>ezetimibe<\/strong>, or <strong>PCSK9 inhibitors<\/strong> are insufficient or not tolerated, <strong>lipoprotein apheresis<\/strong> offers a highly effective and well-tolerated alternative.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_hr-be8425a330a90241e1a8c351bcaeb6a5\">\n#top .hr.hr-invisible.av-av_hr-be8425a330a90241e1a8c351bcaeb6a5{\nmargin-top:-80px;\nheight:1px;\n}\n<\/style>\n<div  class='hr av-av_hr-be8425a330a90241e1a8c351bcaeb6a5 hr-invisible  avia-builder-el-7  el_after_av_textblock  avia-builder-el-last  av-desktop-hide av-medium-hide av-small-hide'><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_half-068220c8262444be99a83ad265bdcedb\">\n.flex_column.av-av_one_half-068220c8262444be99a83ad265bdcedb{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-av_one_half-068220c8262444be99a83ad265bdcedb av_one_half  avia-builder-el-8  el_after_av_one_half  el_before_av_one_half  first flex_column_div av-zero-column-padding column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-1338a7159840966c8035f30034a3d907\">\n#top .av-special-heading.av-av_heading-1338a7159840966c8035f30034a3d907{\npadding-bottom:50px;\n}\nbody .av-special-heading.av-av_heading-1338a7159840966c8035f30034a3d907 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-1338a7159840966c8035f30034a3d907 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-1338a7159840966c8035f30034a3d907 av-special-heading-h3 blockquote modern-quote  avia-builder-el-9  el_before_av_textblock  avia-builder-el-first '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >What is Lipoprotein Apheresis?<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-av_textblock-7a1af7d8f9790576b1769c0a9f0449ed'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>Lipoprotein apheresis<\/strong> (also known as <strong>Lp(a) apheresis<\/strong>) is a specialized blood purification procedure that selectively removes harmful lipids such as <strong>Lipoprotein(a)<\/strong>, <strong>LDL cholesterol<\/strong>, and <strong>triglycerides<\/strong> from the plasma. <\/p>\n<p>This therapy can slow the progression of <strong>atherosclerosis<\/strong> and significantly reduce the risk of <strong>major cardiovascular events<\/strong>.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-a076e89aad9d971e6c4c95a202e2d4a2\">\n#top .av-special-heading.av-av_heading-a076e89aad9d971e6c4c95a202e2d4a2{\npadding-bottom:50px;\n}\nbody .av-special-heading.av-av_heading-a076e89aad9d971e6c4c95a202e2d4a2 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-a076e89aad9d971e6c4c95a202e2d4a2 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-a076e89aad9d971e6c4c95a202e2d4a2 av-special-heading-h3 blockquote modern-quote  avia-builder-el-11  el_after_av_textblock  el_before_av_textblock '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >When is Lipoprotein Apheresis Recommended?<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-av_textblock-7a1af7d8f9790576b1769c0a9f0449ed'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Lipoprotein apheresis is typically indicated for <strong>high-risk patients<\/strong> who do not achieve adequate results with standard lipid-lowering therapy:<\/p>\n<ul>\n<li><strong>Established Atherosclerotic Cardiovascular Disease (ASCVD)<\/strong><br \/>\nSuch as <strong>coronary artery disease (CAD), peripheral artery disease (PAD), cerebrovascular disease (CVD),<\/strong> or <strong>aortic valve stenosis<\/strong>, <strong>combined with elevated Lp(a)<\/strong> that persists despite optimal lifestyle and medication-based treatment.\n<\/li>\n<li><strong>Familial Hypercholesterolemia with LDL > 55 mg\/dL<\/strong><br \/>\nIf <strong>LDL cholesterol<\/strong> levels remain high despite maximum lipid-lowering therapy, lipoprotein apheresis can help reduce cardiovascular risk in genetically predisposed individuals.<\/li>\n<li><strong>Statin Intolerance or Insufficient Response to Lipid-Lowering Therapy<\/strong><br \/>\nFor patients who cannot tolerate statins or do not reach target lipid levels, apheresis offers a safe and effective alternative to further reduce<strong> LDL-C<\/strong> and <strong>Lp(a)<\/strong>.<\/li>\n<\/ul>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_hr-be8425a330a90241e1a8c351bcaeb6a5\">\n#top .hr.hr-invisible.av-av_hr-be8425a330a90241e1a8c351bcaeb6a5{\nmargin-top:-80px;\nheight:1px;\n}\n<\/style>\n<div  class='hr av-av_hr-be8425a330a90241e1a8c351bcaeb6a5 hr-invisible  avia-builder-el-13  el_after_av_textblock  avia-builder-el-last  av-desktop-hide av-medium-hide av-small-hide'><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_half-e671fab5613f317ef63eb9ab712c64a3\">\n.flex_column.av-av_one_half-e671fab5613f317ef63eb9ab712c64a3{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-av_one_half-e671fab5613f317ef63eb9ab712c64a3 av_one_half  avia-builder-el-14  el_after_av_one_half  avia-builder-el-last  flex_column_div av-zero-column-padding column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-88ec11db1686d3548de2512b25770e73\">\n#top .av-special-heading.av-av_heading-88ec11db1686d3548de2512b25770e73{\npadding-bottom:50px;\n}\nbody .av-special-heading.av-av_heading-88ec11db1686d3548de2512b25770e73 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-88ec11db1686d3548de2512b25770e73 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-88ec11db1686d3548de2512b25770e73 av-special-heading-h3 blockquote modern-quote  avia-builder-el-15  el_before_av_textblock  avia-builder-el-first '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >Scientific Evidence for Lipoprotein Apheresis<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-av_textblock-7a1af7d8f9790576b1769c0a9f0449ed'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Numerous clinical studies have demonstrated the <strong>safety and effectiveness <\/strong>of lipoprotein apheresis in reducing <strong>Lp(a)<\/strong> and <strong>LDL cholesterol <\/strong>in high-risk cardiovascular patients:<\/p>\n<p><em>&#8220;\u201cIt was concluded that lipoprotein apheresis is a safe and effective technique that could be considered in the management of hypercholesterolemia and future risk&#8221;<br \/>\n<small><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30799420\/\" rel=\"noopener\" target=\"_blank\">Raina R, et al. Role of Lipoprotein Apheresis in Cardiovascular Disease Risk Reduction. Blood Purif. 2019 <\/a><\/small><\/em><\/p>\n<p><em>&#8220;Lipoprotein apheresis not only reduces LDL-C and Lp(a) levels, but also inflammatory and coagulation markers. It is both anti-atherosclerotic and anti-thrombotic \u2013 making it an ideal option to reduce MACE and MANCE.&#8221;<br \/>\n<small><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11789-019-00094-4\" rel=\"noopener\" target=\"_blank\">Schettler, V.J.J., et al. Lipoprotein apheresis is an optimal therapeutic option to reduce increased Lp(a) levels. Clin Res 2019<\/a><\/small><\/em><\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-f102884d976349ee5ff6921d44c7bf9c\">\n#top .av-special-heading.av-av_heading-f102884d976349ee5ff6921d44c7bf9c{\npadding-bottom:50px;\n}\nbody .av-special-heading.av-av_heading-f102884d976349ee5ff6921d44c7bf9c .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-f102884d976349ee5ff6921d44c7bf9c .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-f102884d976349ee5ff6921d44c7bf9c av-special-heading-h3 blockquote modern-quote  avia-builder-el-17  el_after_av_textblock  el_before_av_textblock '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >Who Can Benefit from Lipoprotein Apheresis?<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-av_textblock-7a1af7d8f9790576b1769c0a9f0449ed'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><ul>\n<li><strong>Elevated Lp(a)<\/strong> despite diet, exercise, and medication<\/li>\n<li><strong>Familial hypercholesterolemia<\/strong> with <strong>LDL > 55 mg\/dL<\/strong><\/li>\n<li><strong>Intolerance to statins<\/strong> or insufficient response to lipid-lowering therapy<\/li>\n<li><strong>Established cardiovascular disease (ASCVD)<\/strong> with persistent lipid abnormalities<\/li>\n<\/ul>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_hr-be8425a330a90241e1a8c351bcaeb6a5\">\n#top .hr.hr-invisible.av-av_hr-be8425a330a90241e1a8c351bcaeb6a5{\nmargin-top:-80px;\nheight:1px;\n}\n<\/style>\n<div  class='hr av-av_hr-be8425a330a90241e1a8c351bcaeb6a5 hr-invisible  avia-builder-el-19  el_after_av_textblock  avia-builder-el-last  av-desktop-hide av-medium-hide av-small-hide'><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p><\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/pages\/724"}],"collection":[{"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/comments?post=724"}],"version-history":[{"count":9,"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/pages\/724\/revisions"}],"predecessor-version":[{"id":831,"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/pages\/724\/revisions\/831"}],"wp:attachment":[{"href":"https:\/\/apherese-kortumpark.de\/en\/wp-json\/wp\/v2\/media?parent=724"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}